Lamivir

Lamivir (Lamivudine) is indicated for use in conjunction with other antiretroviral medicines to treat HIV-1 infections. It works by stopping the virus from spreading and destroying CD4 helper cells. This medicine is classified as a nucleoside analog and its mechanism of action involves blocking the action of the viral RT (reverse transcriptase, an enzyme that the virus needs to replicate), and this results in the termination of the viral DNA chain. The HIV virus can develop a resistance to drugs, and a particular type of mutation of which occurs in the reverse transcriptase gene (called the M184V mutation) may occur if this medicine is used on its own. Resistance can reduce the effectiveness of the medicine, and to combat this, your physician will also advice concomitant treatment with other medicines to ensure that the infection is kept under control.

Lamivir (Lamivudine) tablets are provided as a 150mg strength formula, and dosage is by means of oral administration. Patients may take it without regard to meals, however those who find it difficult to swallow the tablet should contact their physician for advice. It is essential that no doses are missed, as doing so could increase the likelihood of developing viral resistance. Your physician will calculate the right dosage for you. In most cases, adults treating an infection caused by HIV will be told to administer 150mg (one tablet) twice per day, and your physician will also decide for you (based on your unique circumstances) what other antiretroviral medicines you need to take. Strict compliance with the physician`s instructions is required at all times.

Patients who take Lamivir (Lamivudine) might suffer from side effects, such as:

• Insomnia
• Dyspepsia
• Blocked nose
• Concentration problems
• Cramps which affect the abdomen

It is vital that a physician is kept informed of all side effects which occur throughout the course of treatment. The occurrence of serious and harmful reactions is generally considered to be less common, however all patients are advised to be aware of this risk. Visit your physician or attend the emergency room straight away should you suffer from fever, discolored urine, weakness or any other severe side effects that have not been referenced here.

Lamivir (Lamivudine) cannot cure HIV. Therefore, patients are still able to infect others. Precautions such as practicing safe sex can ensure that the risk of infecting others is minimized.

Serious risks associated with this medicine include liver disease (which has the potential to be fatal) and lactic acidosis. Ensure that you discuss the risks of this with your physician prior to commencing treatment.