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Symbal (Duloxetine Hydrochloride) is used for depression, fibromyalgia and musculoskeletal pain. It works by inhibiting pain, relieving anxiety and affecting neurotransmitters in the brain. This medicine is referred to as a serotonin norepinephrine reuptake inhibitor, and its effects on the reuptake of dopamine are said to be considerably less potent. Experts have stated that by normalizing the chemical balance in the brain, it can help to alleviate dysphoric feelings, a lack of interest in hobbies, fatigue and other depressive symptoms. Its anxiolytic effects also make it useful for GAD (generalized anxiety disorder). When used for fibromyalgia, it may work by affecting the nervous system and neural networks of the CNS so as to relieve pain.
Symbal (Duloxetine Hydrochloride) comes as either 20mg, 30mg or 40mg strength tablets for oral administration. The most appropriate dosage schedule will be decided upon by your physician, based on which condition you are treating (pain, depression or anxiety). Adult patients being treated for major depressive disorder may be instructed by their physician to take a starting dosage ranging from 40mg per day (as 2 separate 20mg doses) to 60mg per day (either as a single dose or else 2 doses consisting of 30mg). It can be taken with or without food. Patients must always comply with the dosage instructions given by their physician.
Patients using the antidepressant Symbal (Duloxetine Hydrochloride) may suffer from some side effects, including:
Report all side effects to your physician. There is a possibility that some people treated with this medicine may experience reactions which are severe and could pose a threat to the health. You will need emergency hospitalization or the attention of your physician immediately if you notice a painful sensation occurring when urinating, problems relating to concentration or memory, muscular rigidity, abnormal reflexes, bruises or any other severe reactions that have not been listed here.
Symbal (Duloxetine Hydrochloride) may place some people (especially younger patients) at an increased risk of suicidal ideation or behavior. Ask your physician about this before beginning treatment, and if any strange changes in behavior occur while taking this medicine, consult your physician immediately.
Physicians instruct patients who have been treated with an MAO inhibitor (a type of medicine) within the last 14 days not to take this medicine, due to the fact that doing so may result in a serious drug reaction. Also, patients will be told by their physician not to take an MAO for a specified period of time after treatment with this medicine is stopped.